Group

Mission

We will conduct interdisciplinary research in the field of protein engineering. We wish to understand the structure-function relationships of proteins and improve their functionalities for biotechnologies. We study molecular mechanisms of neurodegenerative diseases, including Alzheimer’s and Parkinson’s disease.

Our goal is to be recognized as one of the leading protein engineering groups in Europe. We will consistently strive to publish our findings in reputable scientific journals, develop new software tools and microfluidic platforms and apply research results to practice.

The key components of our daily activities will include collaboration between experimentalists and theoreticians, solidarity among the laboratory team and mentoring of young colleagues—all while maintaining a friendly and creative working environment to honor the name of Jan Josef Loschmidt.

Values

Team members are available to each other in a way that differs from normal indifferent civility.

The activity takes place in the atmosphere of informality and general awareness.

The members of the team have developed a feeling of belonging which includes a jointly shared contentment when things are going well or a common concern when going less well.

The actual team is democratic. Among the team members there are no differences. That does not mean, however, that anarchy reigns.

The desire for self-improvement is evident, the central idea is the quality of one’s work.

Formulated by Prince George

History

The group was established in 1994. The first research project focused on the development of structure-biodegradability relationships and was financially supported by the European Union. The first research facilities were purchased due to the collaboration with the bioremediation company Inpost Ltd.

The Josef Loschmidt Chair was established at the Faculty of Science of Masaryk University by a donation of Alfred and Isabel Bader to honor the name of a great Czech scientist of the 19th century, Jan Josef Loschmidt. Jiri Damborsky was appointed to the Chair in 2003 and Loschmidt Laboratories were founded two years later. The Laboratories hold prestigious awards from the European Molecular Biology Organization and the American foundation Howard Hughes Medical Institute.

The first biotechnology spin-off of Masaryk University, Enantis Ltd., was founded by the members of Loschmidt Laboratories in 2006 and the software spin-off company CaverSoft in 2011. Since 2008, Loschmidt Laboratories are part of the Department of Experimental Biology and the Research Centre for Toxic Compounds in the Environment. Since 2011, we are affiliated also to the International Clinical Research Center at St. Anne’s University Hospital.

Andrea Schenkmayerova received a grant to attend an EMBO Practical Course
Open Postdoc Position: Protein Engineering
FireProt in MUNI
Jan Stourac won Dean’s Award
Jan Stourac and Ondrej Vavra Masters of Science
An article co-authored by our group among the most influential articles of 2016
Martin Toul among the top five in biology/biochemistry category of Sigma-Aldrich competition