Method of Production of Optically Active Hydrocarbons and Alcohols Using Hydrolytic Dehalogenation Catalysed by Haloalkane Dehalogenases
Prokop, Z., Damborsky, J., Nagata, Y., Janssen, D.B.
Masaryk University, Žerotínovo nám. 9, 601 77 Brno, Czech Republic
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This invention relates to method for production of optically active haloalkanes, haloalcohols, alcohols, halopolyols and polyols by hydrolytic dehalogenation catalysed by the enzymes haloalkane dehalogenases (Enzyme Commission number EC 220.127.116.11) isolated from microorganisms or altered haloalkane dehalogenases with improved substrate specificity, stereo- or regio-selectivity.