Method of Production of Optically Active Hydrocarbons and Alcohols Using Hydrolytic Dehalogenation Catalysed by Haloalkane Dehalogenases
Authors
Prokop, Z., Damborsky, J., Nagata, Y., Janssen, D.B.
Applicant
Masaryk University, Žerotínovo nám. 9, 601 77 Brno, Czech Republic
Application number
PCT/CZ2005/000099
Date of submission
2004-11-27
Date of publication
Abstract
This invention relates to method for production of optically active haloalkanes, haloalcohols, alcohols, halopolyols and polyols by hydrolytic dehalogenation catalysed by the enzymes haloalkane dehalogenases (Enzyme Commission number EC 3.8.1.5) isolated from microorganisms or altered haloalkane dehalogenases with improved substrate specificity, stereo- or regio-selectivity.