Substituted Aminothiazoles as Inhibitors of Nucleases
Authors
Paruch, K., Carbain, B., Havel, S., Damborský, J., Brezovský , J., Daniel, L.; Sisáková, A.; Nikulenkov, F., Krejčí, L.
Applicant
Masaryk University, Žerotínovo nám. 9, 601 77 Brno, Czech Republic
Application number
US 11,584,742 B2
Date of submission
2019-04-15
Date of publication
2023-02-21
Abstract
Compounds represented by the structural formula (1) R1, R2, R3, R4, R5, R6 are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.