Profile
Research interests
Naina aims to gain a comprehensive understanding of thrombolytic agents and enhance their thrombolytic properties through the rational design of mutants. She studies potential staphylokinase (SAK) mutants, screening them, and analyzing their performance. She employs the hydrogen-deuterium exchange method coupled with mass spectrometry (HDX-MS) to investigate the dynamics of structural changes in SAK apo form and holo form with interaction partners. Additionally, she involves in the preparation and purification of recombinant proteins used for HDX-MS. She also conducts biochemical experiments to evaluate the protein's fibrin selectivity, immunogenicity, half-life, and catalytic activity and compares the experimental data with molecular dynamics simulations.Education
2022 M.Sc., Applied Microbiology, Banaras Hindu University, India2020 B.Sc., Microbiology Honours, Gargi College, University of Delhi, India
Research stays
2022 Environment Biotechnology laboratory, CSIR-Indian Institute of Toxicology Research, Lucknow, IndiaAwards
2022 Gold medal for securing the first rank in the Master’s programme, Banaras Hindu University, India2022 DBT Junior Research Fellowship, Department of Biotechnology, New Delhi, India