Degradation of b-Hexachlorocyclohexane by Haloalkane Dehalogenase LinB from Sphingomonas paucimobilis UT26

Authors

Nagata, Y., Prokop, Z., Sato, Y., Jerabek, P., Kumar, A., Ohtsubo, Y., Tsuda, M., Damborsky, J.

Source

APPLIED AND ENVIRONMENTAL MICROBIOLOGY 71: 2183-2185 (2005)

Abstract

b-Hexachlorocyclohexane (b-HCH) is the most recalcitrant among the a-, b-, g-, and d-isomers of HCH, and causes serious environmental pollution problems. We demonstrate here that the haloalkane dehalogenase LinB, reported earlier to mediate the second step in the degradation of g-HCH in Sphingomonas paucimobilis UT26, metabolizes b-HCH to produce 2,3,4,5,6-pentachlorocyclohexanol.

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Citation

Nagata, Y., Prokop, Z., Sato, Y., Jerabek, P., Kumar, A., Ohtsubo, Y., Tsuda, M., Damborsky, J., 2005: Degradation of b-Hexachlorocyclohexane by Haloalkane Dehalogenase LinB from Sphingomonas paucimobilis UT26. Applied and Environmental Microbiology 71: 2183-2185.

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