Homology Modelling of the Haloalkane Dehalogenase of Sphingomonas paucimobilis UT26
Authors
Damborsky, J., Bull, A. and Hardman, D.
Source
BIOLOGIA 50: 523-528 (1995)
Abstract
The hypothetical three-dimensional structure of the enzyme – 1,3,4,6-tetrachloro-1,4-cyclohexadiene hydrolase – isolated from the strain Sphingomonas paucimobilis UT26 was modelled. Hydrolytic dehalogenase from another bacterial strain (Xanthobacter autotrophicus GJ10), previously studied by X-ray analysis, was used as a reference structure. Differences between the residues in the active site cavity of both enzymes have been related to their substrate activity.