{"id":641,"date":"2013-01-29T13:01:29","date_gmt":"2013-01-29T13:01:29","guid":{"rendered":"http:\/\/loschmidt.chemi.muni.cz\/peg\/?page_id=641"},"modified":"2026-06-12T06:52:00","modified_gmt":"2026-06-12T06:52:00","slug":"diploma-theses","status":"publish","type":"page","link":"https:\/\/loschmidt.chemi.muni.cz\/peg\/courses\/diploma-theses\/","title":{"rendered":"Diploma Theses"},"content":{"rendered":"\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Name<\/th>\nThesis<\/th>\n<\/tr>\n
Richter Martin<\/td>\nResolving Enzymatic Mechanisms for Ligand-Binding Experimental Data Using Machine Learning (Computational Biology and Biomedicine, RECETOX, 2024-2026)<\/td>\n<\/tr>\n
Kapustova Linda<\/td>\nIdentification and Study of Potential Drugs Targeting Apolipoprotein E4 in Alzheimer’s Disease Using Molecular Modelling Methods (Bioinformatics, Department of Biochemistry, 2024-2025)<\/td>\n<\/tr>\n
Svobodova Lucie<\/td>\nWeb Application for the Search of Related Enzymes (FIT VUT, 2024-2025)<\/td>\n<\/tr>\n
Pailozian Karen<\/td>\nPrediction of Protein Stability by Advanced Machine Learning Methods (Bioinformatics, Department of Biochemistry, 2023-2025)<\/td>\n<\/tr>\n
Kabourek Petr<\/td>\nLLWS: Multi-Platform Framework for Distributed Calculation and Its Integration in Fireprotweb 2 a Web-Based Platform for Design of Thermostable Proteins (Department of Computer Systems and Communications, FI MU, 2023-2025)<\/td>\n<\/tr>\n
Havlasek Martin<\/td>\nDevelopment of a Strategy for the Suppression of Protein Aggregation and Its Application to the Dehalogenase LinB (Department of Biochemistry, 2023-2025)<\/td>\n<\/tr>\nOrel Vojtech<\/td>\nKinetic Mechanism of NanoLuc Luciferase (Department of Biochemistry, 2022-2024)<\/td>\n<\/tr>\n
Kopriva Martin<\/td>\nApplication of Microfluidics in Development of Drugs against Alzheimer’s Disease (Department of Biochemistry, 2022-2024)<\/td>\n<\/tr>\n
Lacko David<\/td>\nMachine Learning-based Prediction of Mutational Effects on Protein Immunogenicity (FIT VUT, 2020-2024)<\/td>\n<\/tr>\n
Berezny Matej<\/td>\nBenchmark of the Computational Tools for the Prediction of the Effect of Mutations on Protein Stability (FIT VUT, 2022-2024)<\/td>\n<\/tr>\n
Rosinska Monika<\/td>\nPrediction of the Effect of Mutations on Protein Stability (FIT VUT, 2022-2024)<\/td>\n<\/tr>\n
Smrckova Anna<\/td>\nStructural and Biochemical Characterization of the Renilla<\/italics>-encoded BRET Complex (Department of Experimental Biology, 2020-2024)<\/td>\n<\/tr>\n
Borko Simeon<\/td>\nAnalysis of Cancer-Associated Protein Mutations (Department of Information Systems, FIT VUT, 2020-2023)<\/td>\n<\/tr>\n
Pluskal Daniel<\/td>\nEngineering of a Macromolecular Bioluminescence Resonance Energy Transfer Complex (Department of Biochemistry, 2021-2023)<\/td>\n<\/tr>\n
Faldynova Hana<\/td>\nStudy of the Effect of Mutations on Protein Solubility (Department of Molecular Biology and Genetics, 2021-2023)<\/td>\n<\/tr>\n
Kohout Petr<\/td>\nIdentification of the Protein Tunnels using Molecular Dynamics (Department of Information Systems, FIT VUT, 2020-2022)<\/td>\n<\/tr>\n
Kohout Pavel<\/td>\nApplication of Variational Autoencoders for Ancestral Sequence Reconstruction (Department of Computer Systems, FIT VUT, 2020-2022)<\/td>\n<\/tr>\n
Bubenik Michal<\/td>\nMachine-Learning based Prediction of Substrate Specificity Profiles for Haloalkane Dehalogenases (RECETOX, 2020-2022)<\/td>\n<\/tr>\n
Slanska Michaela<\/td>\nKinetic Mechanism of Fluorinase from Bacterium Streptomyces<\/em> sp. MA37 (Department of Biochemistry, 2020-2022)<\/td>\n<\/tr>\n
Slanska Katerina<\/td>\nStudy of Protein Solubility (Department of Experimental Biology, 2019-2021)<\/td>\n<\/tr>\n
Horackova Jana<\/td>\nPrediction of Stable Proteins (Department of Biochemistry, 2019-2021)<\/td>\n<\/tr>\n
Dobias Adam<\/td>\nPredictSNP Onco: Web Server for Automatic Analysis of Oncology-Based Mutations (Department of Biochemistry, 2018-2021)<\/td>\n<\/tr>\n
Velecky Jan<\/td>\nPrediction of the Effect of Mutation on Protein Solubility Using Electrostatic Potential (Department of Computer Systems, FIT VUT, 2018-2020)<\/td>\n<\/tr>\n
Vasina Michal<\/td>\nHigh-throughput Characterization of Novel Biocatalysts by Using Microfluidics (Department of Biophysical Chemistry, 2017-2019)<\/td>\n<\/tr>\n
Solansky Pavel<\/td>\nApplication of Microfluidics in Metabolic Engineering (Department of Experimental Biology, 2016-2018)<\/td>\n<\/tr>\n
Toul Martin<\/td>\nKinetic Mechanism of Coelenterazine-Dependent Luciferase Reaction (Department of Biochemistry, 2016-2018)<\/td>\n<\/tr>\n
Dockalova Veronika<\/td>\nDevelopment of Fluorescent Substrates for Enzymology (Department of Biophysics, 2016-2018)<\/td>\n<\/tr>\n
Dunajova Zuzana<\/td>\nComputational Engineering of Enzymes with Buried Active Sites (Department of Structural Chemistry, 2015-2018)<\/td>\n<\/tr>\n
Markova Klara<\/td>\nStructural and Functional Characterization of Selected Haloalkane Dehalogenase Variants (Department of Special Biology, 2016-2018)<\/td>\n<\/tr>\n
Stourac Jan<\/td>\nSoftware Tool for Automated Design of Mutations and Smart Libraries for Protein Engineering (Department of Bioinformatics, 2015-2017)<\/td>\n<\/tr>\n
Vavra Ondrej<\/td>\nMethods for Identification of Biologically Relevant Tunnels in Proteins (Department of Genomics and Proteomics, 2015-2017)<\/td>\n<\/tr>\n
Kunka Antonin<\/td>\nStructural Base of Protein Stabilisation (Department of Biochemistry, 2014-2016)<\/td>\n<\/tr>\n
Musil Milos<\/td>\nPredictor of the Effect of Amino Acid Substitutions on Protein Function (Department of Information Systems, Brno University of Technology, 2014-2015)<\/td>\n<\/tr>\n
Szelcsanyiova Petra<\/td>\nBiochemical Characterization of Haloalkane Dehalogenases with Modified Tunnels (Department of Microbiology, 2012-2014)<\/td>\n<\/tr>\n
Buryska Tom<\/td>\nDevelopment of Dehalogenase Inhibitors \u2013 Potential Antituberculotics (Department of Biochemistry, 2011-2013)<\/td>\n<\/tr>\n
Neuwirth Ondrej<\/td>\nDevelopment of Inhibitors of Dehalogenases \u2013 Potential Antituberculotics (Department of Biochemistry, 2010-2013)<\/td>\n<\/tr>\n
Chrast Lukas<\/td>\nCharacterization of Novel Biocatalysts from Extremophilic Bacteria (Department of Microbiology and Molecular Biotechnology, 2010-2012)<\/td>\n<\/tr>\n
Drienovska Ivana<\/td>\nBiochemical Characterization of the First Haloalkane Dehalogenase DpcA Isolated From Extremophilic Organism (Department of Biochemistry, 2011-2012)<\/td>\n<\/tr>\n
Daniel Lukas<\/td>\nIn Silico Study<\/i> of Substrate Specificity of Haloalkane Dehalogenases (Department of Biochemistry, 2009-2011)<\/td>\n<\/tr>\n
Wolny Rostislav<\/td>\nDevelopement of Bioinformatics Server (Faculty of Informatics, 2008-2010)<\/td>\n<\/tr>\n
Dvorak Pavel<\/td>\nDirected Evolution of Haloalkane Dehalogenase DhaA towards Increased
\nActivity with 1,2-dichloroethane (Department of Microbiology, 2008-2009)<\/td>\n<\/tr>\n
Polinek Jiri<\/td>\nFermentative Production of Haloalkane Dehalogenases (Department of Microbiology, 2008-2009)<\/td>\n<\/tr>\n
Pavelka Antonin<\/td>\nHotSpot
\nWizard – Tool for Selection of Protein Engineering Hot Spots (Faculty of Informatics, 2007-2008)<\/td>\n<\/tr>\n
Stepankova Veronika<\/td>\nMedium Engineering of Haloalkane Dehalogenase Catalysis: Effect of Water-Miscible Organic Solvents (Department of Biochemistry, 2005-2008)<\/td>\n<\/tr>\n
Holub Peter<\/td>\nProtein Engineering of Haloalkane Dehalogenase LinB: Towards the Change of Reaction Mechanism (Department of Biochemistry, 2006-2008)<\/td>\n<\/tr>\n
Jerabek Petr<\/td>\nMolecular Modeling of Enantioselectivity of Haloalkane Dehalogenase LinB (Department of Biochemistry, 2005-2007)<\/td>\n<\/tr>\n
Bidmanova Sarka<\/td>\nDevelopment and Construction of Biosensors for Detection of Halogenated Compounds in the Environment (Department of Microbiology, 2005-2007)<\/td>\n<\/tr>\n
Brezovsky Jan<\/td>\nComputer-Assisted Study of Enzymatic Dehalogenation of DDT (Department of Biophysics, 2005-2006)<\/td>\n<\/tr>\n
Klvana Martin<\/td>\nComputer Modelling of Bacterial Enzymes Involved in Degradation of Halogenated Hydrocarbons (Department of Microbiology, 2002-2004)<\/td>\n<\/tr>\n
Tesinska Iva<\/td>\nMycobacterial Haloalkane Dehalogenases Rv2296 and Rv2579 (Department of Biochemistry, 2002-2004)<\/td>\n<\/tr>\n
Dobes Petr<\/td>\nStructure-Function Characterization of the Elicitin Cryptogein (Department of Biochemistry, 2001-2003)<\/td>\n<\/tr>\n
Budova Martina<\/td>\nExprese, purifikace a kineticka charakterizace haloalkan dehalogenas (Department of Biochemistry, 2001-2002)<\/td>\n<\/tr>\n
Jedlicka Tomas<\/td>\nPocitacove modelovani enzym-substrat komplexu haloalkan dehalogenaz (Department of Environmental Sciences and Ecotoxicology, 2000-2003)<\/td>\n<\/tr>\n
Strouhal Michal<\/td>\nScreening of Genes rv2579, rv2296<\/i> and dhmA<\/i> in Isolates of M. bovis, M. avium<\/i> a M. paratuberculosis<\/i> (Department of Microbiology, 2000-2003)<\/td>\n<\/tr>\n
Monincova Marta<\/td>\nStudy of Kinetics of Microbial Dehalogenation Reactions (Department of Microbiology, 2000-2002)<\/td>\n<\/tr>\n
Marvanova Sona<\/td>\nBiochemical Characterization of Mutant Haloalkane Dehalogenases (Department of Environmental Sciences and Ecotoxicology, 1999-2001)<\/td>\n<\/tr>\n
Czernekova Vladka<\/td>\nPurification of Dehalogenase from Bacterium Mycobacterium avium<\/i> (Department of Biochemistry, 1999-2001)<\/td>\n<\/tr>\n
Slanina Michal<\/td>\nHydrolytic Dehalogenation of Unsaturated Aliphatic Hydrocarbons (Department of Environmental Sciences and Ecotoxicology, 1998-1999)<\/td>\n<\/tr>\n
Bohac Michal<\/td>\nComputer Modelling of Dehalogenation Reactions of Haloalkane Dehalogenases (Department of Environmental Sciences and Ecotoxicology, 1997-2000)<\/td>\n<\/tr>\n
Prokop Martin<\/td>\nTRITON – Visualization Software for Study of Enzymatic Reactions (Department of Organic Chemistry, 1995-1997)<\/td>\n<\/tr>\n
Hynkova Kamila<\/td>\nEstimation of Steady-State Constants of Haloalkane Dehalogenase LinB for Group of Halogenated Hydrocarbons (Department of Environmental Sciences and Ecotoxicology, 1995-1997)<\/td>\n<\/tr>\n
Jesenska Andrea<\/td>\nStudy of Structure-Biodegradability Relationships for Halogenated Aliphatic Hydrocarbons (Department of Microbiology, 1995-1997)<\/td>\n<\/tr>\n
Blaha Ludek<\/td>\nApplications of Bioluminiscence Test (Department of Microbiology, 1994-1996)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"

Name Thesis Richter Martin Resolving Enzymatic Mechanisms for Ligand-Binding Experimental Data Using Machine Learning (Computational Biology and Biomedicine, RECETOX, 2024-2026) Kapustova Linda Identification and Study of Potential Drugs Targeting Apolipoprotein E4 in Alzheimer’s Disease Using Molecular Modelling Methods (Bioinformatics, Department of Biochemistry, 2024-2025) Svobodova Lucie Web Application for the Search of Related Enzymes (FIT VUT, […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":868,"menu_order":23,"comment_status":"closed","ping_status":"closed","template":"","meta":{"ngg_post_thumbnail":0,"footnotes":""},"class_list":["post-641","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/loschmidt.chemi.muni.cz\/peg\/wp-json\/wp\/v2\/pages\/641","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/loschmidt.chemi.muni.cz\/peg\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/loschmidt.chemi.muni.cz\/peg\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/loschmidt.chemi.muni.cz\/peg\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/loschmidt.chemi.muni.cz\/peg\/wp-json\/wp\/v2\/comments?post=641"}],"version-history":[{"count":54,"href":"https:\/\/loschmidt.chemi.muni.cz\/peg\/wp-json\/wp\/v2\/pages\/641\/revisions"}],"predecessor-version":[{"id":11622,"href":"https:\/\/loschmidt.chemi.muni.cz\/peg\/wp-json\/wp\/v2\/pages\/641\/revisions\/11622"}],"up":[{"embeddable":true,"href":"https:\/\/loschmidt.chemi.muni.cz\/peg\/wp-json\/wp\/v2\/pages\/868"}],"wp:attachment":[{"href":"https:\/\/loschmidt.chemi.muni.cz\/peg\/wp-json\/wp\/v2\/media?parent=641"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}