News
Triple Success at SOC Competition
Tereza Sustrova, Julie Krizkova and Dominika Damborska succeeded in the regional round of the science competition for secondary school students (SOC). Tereza prepared her thesis on „Reprogramming the luciferin-substrate specificity in NanoLuc luciferase” under the supervision of Martin Marek, while Julie’s thesis “On the origin of bioluminescence in the brittle star Amphiura filiformis” was supervised […]
Martin to Present at the Congress of the European Society for Photobiology
Martin Marek is invited to give a talk at the 20th Congress of the European Society for Photobiology, which will be based in Lyon and held in Institut National des Sciences Appliquées from August 27-31, 2023. Martin will present our results in the session dedicated to Bioluminescence.
Marika Awarded the Best Presentation Award
Marika Majerova has been awarded by the Best Presentation Award at the Hot Topics in Contemporary Crystallography 5 Conference on Experimental Advances in Macromolecular Crystallography. The meeting took place in Dubrovnik (Croatia) on 16-21 April 2023. Many congratulations to Marika and her supervisor Martin!
4th Hands-on Computational Enzyme Design Course
Our Hands-on Computational Enzyme Design Course has a full capacity! We accepted 25 in-person and 30 online participants from 100 applications. Two winners of scholarships were selected from 11 applications. We are looking forward to seeing you at the end of May!
Honza to Present at ESOC 2023
Honza Mican will present E-Poster at the forthcoming 9th European Stroke Organisation Conference (ESOC), which will be taking place in Munich, Germany, on 24 – 26 May 2023. ESOC is Europe’s leading forum for advances in research and clinical care of patients with cerebrovascular diseases. Honza will introduce “Protein Engineering of Staphylokinase with Improved Thrombolysis”.
Vesicles Mimicking Neuron Plasma Membranes Successfully Produced
Giant Unilamellar Vesicles (GUVs) have been successfully produced using a microfluidic chip in our lab. Produced GUVs with specific compositions mimicking neuron plasma membranes will help to study the molecular pathogenesis of Alzheimer’s disease. Sincere congratulations to Jan C., Martin K., Anthony, David, and Zbynek and big thanks to our collaborators from ETH Zürich.
4th Hands-on Computational Enzyme Design Workshop
Would you like to delve deeper into protein engineering? Loschmidt Laboratories together with Enantis organize an interactive online course exploring web-based tools suitable for mining new enzymes and engineering enzyme activity, specificity, enantioselectivity, stability and solubility. You will have a chance to learn from the developers of these tools, set up optimal calculations and interpret […]
Mystery of Renilla-type Luciferases Solved
The first LL publication in 2023 has come out in Nature Catalysis! We deciphered the molecular principle of the oxidative mechanism by which Renilla-type luciferases generate blue photons. Read more about this amazing & light-emitting enzyme in the just-published paper “Catalytic Mechanism for Renilla-type Luciferases“. The great news has been shared with the general public: […]
New Baby in LL
Congratulations to Marketa Stuchla and her husband on the birth of their daughter Rebeka (5th January 2023, 3880 g and 51 cm)!
PredictSNP Onco: Towards Personalized Medicine in Children’s Oncology
We are excited to report the hot testing phase of the PredictSNP Onco web tool. This fully automated web tool conducts multiple analyses of mutations potentially connected with cancer development. The user only selects the target protein and mutation. We estimate whether the mutation is deleterious or neutral. We also analyze the effect of a […]