Sergio Manuel Marques, Dr.
Organic and Computational Chemistry
Research interestsSérgio Marques’ main research topic is focused on utilizing molecular modelling tools for protein engineering. He is working on several projects involving the optimization of various properties of enzymes (e.g., haloalkane dehalogenases and dioxygenases) for different practical purposes. He also collaborates with other research groups to understand the catalytic properties of their proteins of interest or design improved variant using computational biology methods. More recently, Sérgio Marques has been involved in applying computational methods for understanding the mechanisms of Alzheimer's disease at the molecular level and the protective effects of small molecules.
Education2007 PhD, Chemistry, Instituto Superior Técnico, Technical University of Lisbon, Lisbon, Portugal
2002 MSc, Chemical Engineering, Instituto Superior Técnico, Technical University of Lisbon, Lisbon, Portugal
Research stays2016 Prof. Michele Parrinello’s group, ETH Zurich (Lugano, Switzerland)
2009 Prof. Adriano Martinelli’s group, University of Pisa (Pisa, Italy)
2007-2008 Prof. Armando Rossello’s group, University of Pisa (Pisa, Italy)
2004 Prof. Claudiu Supuran’s group, University of Florence (Florence, Italy)
TeachingHands-on Computational Enzyme Design Course (2020-now)
Structural Biology and Bioinformatics (2021-now)
Structural Biology (2017-now)
Scientific output56 research articles