Thermostable FGF2 Polypeptide, Use Thereof
Authors
Dvorak, P., Krejci, P., Balek, L., Eiselleova, L., Konecna, Z., Dvorak, P., Bednar, D., Brezovsky, J., Sebestova, E., Chaloupkova, R., Stepankova, V., Vanacek, P., Prokop, Z., Damborsky, J., Bosakova, M.
Applicant
Masaryk University and Enantis, s.r.o., Brno, Czech Republic
Application number
IN485239
Date of submission
2016-10-03
Date of publication
2023-19-12
Abstract
The present invention relates to engineered Fibroblast Growth Factor 2 (FGF2, bFGF) having improved thermal stability compared to the wild-type and the use thereof in the cell biology research, regenerative medicine and related medical applications or cosmetics. The present invention further relates to a culture medium comprising FGF2 suitable for culturing a human pluripotent stem cells involving both human embryonic stem cells and induced pluripotent stem cells.