News
New Collaboration Stanford University
New project will be started with Prof. Kool group from Stanford University. The project will be focused on development of novel fluorescent probes.
New Advisor
We are happy to inform you that Dr. Lubos Janda will start working with us from January, 2017.
Awarded GACR grant
Assoc. Prof. Ivana Kuta-Smatanova, from the University of South Bohemia, and our team leader Dr. Radka Chaloupkova have been awarded a standard grant by the Grant Agency of the Czech Republic. The complete list of supported projects can be found here. The project will focus on study of hydration and flexibility of enzymes. Sincere congratulations […]
The Best Poster
Zuzka Dunajova was awarded for the best poster at the 3rd Workshop on High-Throughput Molecular Dynamics, in Barcelona, Spain on the November, 11, 2016.
Ph.D. Position Filled
DESCRIPTION: Part of the Marie Curie Innovative Training Network ES-Cat, aimed at directed protein evolution for synthetic biology and biocatalysis. The project is an EU-funded collaboration between European laboratories working on protein engineering: http://www.bioc.cam.ac.uk/hollfelder/Research/es-cat. We are seeking a motivated student for a Ph.D. in the Loschmidt Laboratories at the Masaryk University and International Centre For […]
Jaroslav Bendl, Ph.D.
Jaroslav Bendl successfully defended his Ph.D. Thesis “Prediction of the Effect of Amino Acid Substitutions on Protein Function” yesterday. Sincere congratulations and good luck in future projects in the Functional Neurogenomics Lab at Mount Sinai!
Engineering a de Novo Transport Tunnel
Here we describe the computational design and directed evolution of a de novo transport tunnel in a haloalkane dehalogenase. Mutants with a blocked native tunnel and a newly opened auxiliary tunnel in a distinct part of the structure showed dramatically modified properties. The mutants with blocked tunnels acquired specificity never observed with native family members: […]
Researchers’ Night
Loschmidt Laboratories participitated on Researchers’ Night in Brno on the September, 30, 2016.
Dr. Brezovsky the Group Leader in Poland
Dr. Jan Brezovsky was accepted as the new group leader at the International Institute of Molecular and Cell Biology, Warsaw, and at the Institute of Biotechnology and Molecular Biology of the Adam Mickiewicz University, Poznan, Poland. Sincere congratulations and best of luck with establishing a strong scientific team!
PredictSNP in MUNI
The article by Ema Wiesnerova describing our bioinformatics tool PredictSNP, an ensemble-based classifier for prediction of the effect of substitutions, have been published in muni.