Bachelor Theses

Name Thesis
Makuch Tomas Computational Analysis of the FYY Protein (Department of Physics, Biophysics, 2024-2025)
Bryja Matej Analysis of Protein-Protein Interactions Using In Silico Methods With Focus on Thrombolytic Staphylokinase (Department of Biochemistry, Bioinformatics, 2024-2025)
Velatova Nikola Genetic Variants of Apolipoprotein E (ApoE) and Their Roles in Neurodegenerative Diseases (Department of Experimental Biology, Medical Genetics and Molecular Diagnostics, 2021-2025)
Demovic Matej Interpreting Protein Molecular Dynamics Data with Explainable Artificial Intelligence (RCX, Computational Biology and Biomedicine, 2024-2025)
Volf Eduard Machine Learning-Based Tools for Predicting B-cell-dependent Immune Response to Protein-Bbased Therapeutics (Department of Experimental Biology, Medical Genetics and Molecular Diagnostics, 2022-2025)
Kapustova Linda Identification and Study of Potential Drugs Targeting Apolipoprotein E4 in Alzheimer’s Disease Using Molecular Modelling Methods (Department of Biochemistry, 2023-2024)
Havlasek Martin Probing the Limits of Modern Approaches to Protein Stabilization (Department of Biochemistry, 2021-2023)
Kabourek Petr LLWS: REST Backend for Centralized Execution of Bioinformatics Calculations (Department of Computer Systems and Communications, FI MU, 2019-2023)
Pailozian Karen Machine Learning-based Prediction of Protein Melting Temperatures for Discovery of Stable Biocatalysts (Department of Biochemistry, 2020-2023)
Arefiev Ihor Design of Dioxygenases to Catalyze Sesquiterpenes (Department of Biophysics and Medical Informatics, National Taras Shevchenko University of Kyiv, 2022-2023)
Kohutekova Tana Directed Evolution of Enzymes on Microfluidic Chip (Department of Biomedical Engineering, FEKT VUT, 2021-2023)
Jakab Karol Rational Design of Active-Site Loops in Dioxygenases Using Molecular Modelling Methods (Department of Biochemistry, 2021-2023)
Szotkowska Veronika The Study of Protein Unfolding Utilizing Molecular Dynamics Simulation (RECETOX, 2019-2023)
Smrckova Anna Molecular Principles of the Bioluminescence Resonance Energy Transfer and Their Biotechnological Applications (Department of Experimental Biology, 2019-2022)
Lacko David Platform for Biological Sequence Analysis Using Machine Learning (Department of Computer Systems, FIT VUT, 2019-2022)
Pluskal Daniel Biochemical Analysis of a Luciferase Complex (Department of Biochemistry, 2018-2021)
Faldynova Hana Engineering of Protein Solubility (Department of Experimental Biology, 2018-2021)
Marko Julius Prediction of the Effect of Mutation on Protein Solubility
Using Machine Learning (Department of Information Systems, FIT VUT, 2017-2020)
Borko Simeon Identification of Related Enzymes (Department of Information Systems FIT VUT, 2017-2020)
Slanska Michaela Development of Fluorogenic Substrates for Enzyme Kinetics and Protein Labelling (Department of Biochemistry, 2017-2020)
Slanska Katerina Study of Protein Solubility and Aggregation (Department of Biochemistry, 2016-2019)
Fronkova Sabina New Trends in Methodologies for Structural Analysis of Enzymes (Department of Molecular Biology and Genetics, 2018-2020)
Hubacek Michal Utilization of Non-canonical Amino Acids in Protein Engineering (Department of Molecular Biology and Genetics, 2016-2017)
Libichova Lenka Methods for Construction of Smart Mutant Libraries in Protein Engineering (Department of Molecular Biology and Genetics, 2016-2017)
Vasina Michal Application of Microfluidics in Characterisation of Substrate Specificity of Halogenalkane Dehalogenases (Department of Biophysical Chemistry, 2016-2017)
Nemeth Robin Study and Engineering of Tunnels in Proteins (Department of Biochemistry, 2016-2017)
Dockalova Veronika Photophysical Characteristics of Fluorescent Substrates for Enzymology (Department of Condensed Matter Physics, 2015-2016)
Toul Martin Kinetic Mechanism of Ancestral Haloalkane Dehalogenase (Department of Biochemistry, 2015-2016)
Markova Klara Crystallization and Structural Characterization of Stable Variants of Haloalkane Dehalogenase DhaA (Department of Experimental Biology, 2015-2016)
Solansky Pavel Application of Microfluidics in Metabolic Engineering (Department of Experimental Biology, 2015-2016)
Stourac Jan A System for Integration of Bioinformatics Tools for Analyzing Protein Tunnels (Department of Computer Systems and Communications, 2014-2015)
Korenciakova Zuzana Development of Fluorescent Substrates for Enzymologic Applications (Department of Biophysical Chemistry, 2014-2015)
Vavra Ondrej Correlated Mutations in Proteins (Department of Experimental Biology, 2013-2014)
Kunka Antonin Inhibitors of Halogenalkane Dehalogenases as Potential Antituberculotics (Department of Biochemistry, 2013-2014)
Surgentova Marta Computational Analysis of Protein Tunnels (Institute of Biostatistics and Analyses, 2012-2013)
Szelcsanyiova Petra Screening of Isolated or Evolved Biocatalysts with High Stability a Activity In vitro and In vivo (Department of Microbiology and Molecular Biotechnology, 2011-2012)
Buryska Tomas Developement of Haloalkane Dehalogenase Inhibitors (Department of Biochemistry, 2010-2011)
Ghazalova Tereza Teoretical Tools for Engineering of Protein Tunnels (National Centre for Biomolecular Research, 2010-2011)
Modrava Veronika Virtual Screening of Biologically Active Compounds (National Centre for Biomolecular Research, 2010-2011)
Tischler Jakub Prediction of Effect of Amino Acid Substitution on Protein Function (Research Centre for Toxic Compounds in the Environment, 2010-2011)
Harnos Jakub Structure, Function and Evolution of Haloalkane Dehalogenases (Department of Experimental Biology, 2010-2011)
Hankeova Simona Effect of Ions on Catalytic Function of Hydrolytic Enzymes (Department of Experimental Biology, 2009-2010)
Bednar David Molecular Modelling of Haloalkane Dehalogenase Activity with Cyclodiene Insecticides (Department of Biochemistry, 2009-2010)
Drienovska Ivana Characterization of Novel Biocatalyst Haloalkane Dehalogenase DhcA from Halophilic Microorganism Hahella chejuensis KCTC 2396 (Department of Biochemistry, 2009-2010)
Matejicek Jiri Calculation of Attributes for Prediction of Effects of Mutation on Protein Function (Brno University of Technology, Faculty of Information Technology, 2008-2009)
Lisak Peter Development of Meta-Server for Prediction of Mutations Effects on Protein Function (Brno University of Technology, Faculty of Information Technology, 2008-2009)
Daniel Lukas Study of Substrate Specificity of Haloalkane Dehalogenases by Virtual Screening (Institute of Experimental Biology, 2008-2009)
Polinek Jiri Novel Bacterial Sources of Haloalkane Dehalogenases and Study of their Function (Department of Microbiology, 2006-2007)
Dvorak Pavel Methods of Directed Evolution: Applications towards Engineering of Haloalkane Dehalogenases (Department of Molecular Biology, 2006-2007)
Stepankova Veronika Medium Engineering of Haloalkane Dehalogenase Catalysis (Department of Biochemistry, 2005-2006)
Moninec Jiri Development of a System for Advertising of Academic Positions (Faculty of Informatics, 2003-2004)
Jerabek Petr Quantum-Mechanics Study of the Dehalogenation of the 1,2,3-trichloropropane by Haloalkane Dehalogenases (Department of Biochemistry, 2003-2004)

Season’s Greetings
Christmas Party
Four New PhD Talents from LL
Lecture of Dr. Zhongyue Yang
Brazilian Patent for FGF2-STAB
David and Martin Received MUNI Scientist Award
Computational Enzyme Design Course is FULL