Bachelor Theses

Name Thesis
Makuch Tomas Computational Analysis of the FYY Protein (Department of Physics, Biophysics, 2024-2025)
Bryja Matej Analysis of Protein-Protein Interactions Using In Silico Methods With Focus on Thrombolytic Staphylokinase (Department of Biochemistry, Bioinformatics, 2024-2025)
Velatova Nikola Genetic Variants of Apolipoprotein E (ApoE) and Their Roles in Neurodegenerative Diseases (Department of Experimental Biology, Medical Genetics and Molecular Diagnostics, 2021-2025)
Demovic Matej Interpreting Protein Molecular Dynamics Data with Explainable Artificial Intelligence (RCX, Computational Biology and Biomedicine, 2024-2025)
Volf Eduard Machine Learning-Based Tools for Predicting B-cell-dependent Immune Response to Protein-Bbased Therapeutics (Department of Experimental Biology, Medical Genetics and Molecular Diagnostics, 2022-2025)
Kapustova Linda Identification and Study of Potential Drugs Targeting Apolipoprotein E4 in Alzheimer’s Disease Using Molecular Modelling Methods (Department of Biochemistry, 2023-2024)
Havlasek Martin Probing the Limits of Modern Approaches to Protein Stabilization (Department of Biochemistry, 2021-2023)
Kabourek Petr LLWS: REST Backend for Centralized Execution of Bioinformatics Calculations (Department of Computer Systems and Communications, FI MU, 2019-2023)
Pailozian Karen Machine Learning-based Prediction of Protein Melting Temperatures for Discovery of Stable Biocatalysts (Department of Biochemistry, 2020-2023)
Arefiev Ihor Design of Dioxygenases to Catalyze Sesquiterpenes (Department of Biophysics and Medical Informatics, National Taras Shevchenko University of Kyiv, 2022-2023)
Kohutekova Tana Directed Evolution of Enzymes on Microfluidic Chip (Department of Biomedical Engineering, FEKT VUT, 2021-2023)
Jakab Karol Rational Design of Active-Site Loops in Dioxygenases Using Molecular Modelling Methods (Department of Biochemistry, 2021-2023)
Szotkowska Veronika The Study of Protein Unfolding Utilizing Molecular Dynamics Simulation (RECETOX, 2019-2023)
Smrckova Anna Molecular Principles of the Bioluminescence Resonance Energy Transfer and Their Biotechnological Applications (Department of Experimental Biology, 2019-2022)
Lacko David Platform for Biological Sequence Analysis Using Machine Learning (Department of Computer Systems, FIT VUT, 2019-2022)
Pluskal Daniel Biochemical Analysis of a Luciferase Complex (Department of Biochemistry, 2018-2021)
Faldynova Hana Engineering of Protein Solubility (Department of Experimental Biology, 2018-2021)
Marko Julius Prediction of the Effect of Mutation on Protein Solubility
Using Machine Learning (Department of Information Systems, FIT VUT, 2017-2020)
Borko Simeon Identification of Related Enzymes (Department of Information Systems FIT VUT, 2017-2020)
Slanska Michaela Development of Fluorogenic Substrates for Enzyme Kinetics and Protein Labelling (Department of Biochemistry, 2017-2020)
Slanska Katerina Study of Protein Solubility and Aggregation (Department of Biochemistry, 2016-2019)
Fronkova Sabina New Trends in Methodologies for Structural Analysis of Enzymes (Department of Molecular Biology and Genetics, 2018-2020)
Hubacek Michal Utilization of Non-canonical Amino Acids in Protein Engineering (Department of Molecular Biology and Genetics, 2016-2017)
Libichova Lenka Methods for Construction of Smart Mutant Libraries in Protein Engineering (Department of Molecular Biology and Genetics, 2016-2017)
Vasina Michal Application of Microfluidics in Characterisation of Substrate Specificity of Halogenalkane Dehalogenases (Department of Biophysical Chemistry, 2016-2017)
Nemeth Robin Study and Engineering of Tunnels in Proteins (Department of Biochemistry, 2016-2017)
Dockalova Veronika Photophysical Characteristics of Fluorescent Substrates for Enzymology (Department of Condensed Matter Physics, 2015-2016)
Toul Martin Kinetic Mechanism of Ancestral Haloalkane Dehalogenase (Department of Biochemistry, 2015-2016)
Markova Klara Crystallization and Structural Characterization of Stable Variants of Haloalkane Dehalogenase DhaA (Department of Experimental Biology, 2015-2016)
Solansky Pavel Application of Microfluidics in Metabolic Engineering (Department of Experimental Biology, 2015-2016)
Stourac Jan A System for Integration of Bioinformatics Tools for Analyzing Protein Tunnels (Department of Computer Systems and Communications, 2014-2015)
Korenciakova Zuzana Development of Fluorescent Substrates for Enzymologic Applications (Department of Biophysical Chemistry, 2014-2015)
Vavra Ondrej Correlated Mutations in Proteins (Department of Experimental Biology, 2013-2014)
Kunka Antonin Inhibitors of Halogenalkane Dehalogenases as Potential Antituberculotics (Department of Biochemistry, 2013-2014)
Surgentova Marta Computational Analysis of Protein Tunnels (Institute of Biostatistics and Analyses, 2012-2013)
Szelcsanyiova Petra Screening of Isolated or Evolved Biocatalysts with High Stability a Activity In vitro and In vivo (Department of Microbiology and Molecular Biotechnology, 2011-2012)
Buryska Tomas Developement of Haloalkane Dehalogenase Inhibitors (Department of Biochemistry, 2010-2011)
Ghazalova Tereza Teoretical Tools for Engineering of Protein Tunnels (National Centre for Biomolecular Research, 2010-2011)
Modrava Veronika Virtual Screening of Biologically Active Compounds (National Centre for Biomolecular Research, 2010-2011)
Tischler Jakub Prediction of Effect of Amino Acid Substitution on Protein Function (Research Centre for Toxic Compounds in the Environment, 2010-2011)
Harnos Jakub Structure, Function and Evolution of Haloalkane Dehalogenases (Department of Experimental Biology, 2010-2011)
Hankeova Simona Effect of Ions on Catalytic Function of Hydrolytic Enzymes (Department of Experimental Biology, 2009-2010)
Bednar David Molecular Modelling of Haloalkane Dehalogenase Activity with Cyclodiene Insecticides (Department of Biochemistry, 2009-2010)
Drienovska Ivana Characterization of Novel Biocatalyst Haloalkane Dehalogenase DhcA from Halophilic Microorganism Hahella chejuensis KCTC 2396 (Department of Biochemistry, 2009-2010)
Matejicek Jiri Calculation of Attributes for Prediction of Effects of Mutation on Protein Function (Brno University of Technology, Faculty of Information Technology, 2008-2009)
Lisak Peter Development of Meta-Server for Prediction of Mutations Effects on Protein Function (Brno University of Technology, Faculty of Information Technology, 2008-2009)
Daniel Lukas Study of Substrate Specificity of Haloalkane Dehalogenases by Virtual Screening (Institute of Experimental Biology, 2008-2009)
Polinek Jiri Novel Bacterial Sources of Haloalkane Dehalogenases and Study of their Function (Department of Microbiology, 2006-2007)
Dvorak Pavel Methods of Directed Evolution: Applications towards Engineering of Haloalkane Dehalogenases (Department of Molecular Biology, 2006-2007)
Stepankova Veronika Medium Engineering of Haloalkane Dehalogenase Catalysis (Department of Biochemistry, 2005-2006)
Moninec Jiri Development of a System for Advertising of Academic Positions (Faculty of Informatics, 2003-2004)
Jerabek Petr Quantum-Mechanics Study of the Dehalogenation of the 1,2,3-trichloropropane by Haloalkane Dehalogenases (Department of Biochemistry, 2003-2004)

Sergio attended 3rd BioExcel Conference
Workshop on Advanced Protein Engineering and Biotherapeutics Development
Celebration of Our New Publication
Martin and Michal at 7th EnzymeML Workshop
Research Internship of Nikitas
Martin at CCP4-BCA Summer School
Hidden Enzymes: Interview with Monika