Diploma Theses

Name Thesis
Kohout Pavel Application of Variational Autoencoders for Ancestral Sequence Reconstruction (Department of Computer Systems, FIT VUT, 2020-2022)
Bubenik Michal Machine-Learning based Prediction of Substrate Specificity Profiles for Haloalkane Dehalogenases (RECETOX, 2020-2022)
Slanska Michaela Kinetic Mechanism of Fluorinase from Bacterium Streptomyces sp. MA37 (Department of Biochemistry, 2020-2022)
Slanska Katerina Study of Protein Solubility (Department of Molecular Biology and Genetics, 2019-2021)
Horackova Jana Prediction of Stable Proteins (Department of Biochemistry, 2019-2021)
Dobias Adam PredictSNP Onco: Web Server for Automatic Analysis of Oncology-Based Mutations (Department of Biochemistry, 2018-2021)
Velecky Jan Prediction of the Effect of Mutation on Protein Solubility Using Electrostatic Potential (Department of Computer Systems, FIT VUT, 2018-2020)
Vasina Michal High-throughput Characterization of Novel Biocatalysts by Using Microfluidics (Department of Biophysical Chemistry, 2017-2019)
Solansky Pavel Application of Microfluidics in Metabolic Engineering (Department of Molecular Biology and Genetics, 2016-2018)
Toul Martin Kinetic Mechanism of Coelenterazine-Dependent Luciferase Reaction (Department of Biochemistry, 2016-2018)
Dockalova Veronika Development of Fluorescent Substrates for Enzymology (Department of Biophysics, 2016-2018)
Dunajova Zuzana Computational Engineering of Enzymes with Buried Active Sites (Department of Structural Chemistry, 2015-2018)
Markova Klara Structural and Functional Characterization of Selected Haloalkane Dehalogenase Variants (Department of Special Biology, 2016-2018)
Stourac Jan Software Tool for Automated Design of Mutations and Smart Libraries for Protein Engineering (Department of Bioinformatics, 2015-2017)
Vavra Ondrej Methods for Identification of Biologically Relevant Tunnels in Proteins (Department of Genomics and Proteomics, 2015-2017)
Kunka Antonin Structural Base of Protein Stabilisation (Department of Biochemistry, 2014-2016)
Musil Milos Predictor of the Effect of Amino Acid Substitutions on Protein Function (Department of Information Systems, Brno University of Technology, 2014-2015)
Szelcsanyiova Petra Biochemical Characterization of Haloalkane Dehalogenases with Modified Tunnels (Department of Microbiology, 2012-2014)
Buryska Tom Development of Dehalogenase Inhibitors – Potential Antituberculotics (Department of Biochemistry, 2011-2013)
Neuwirth Ondrej Development of Inhibitors of Dehalogenases – Potential Antituberculotics (Department of Biochemistry, 2010-2013)
Chrast Lukas Characterization of Novel Biocatalysts from Extremophilic Bacteria (Department of Microbiology and Molecular Biotechnology, 2010-2012)
Drienovska Ivana Biochemical Characterization of the First Haloalkane Dehalogenase DpcA Isolated From Extremophilic Organism (Department of Biochemistry, 2011-2012)
Daniel Lukas In Silico Study of Substrate Specificity of Haloalkane Dehalogenases (Department of Biochemistry, 2009-2011)
Wolny Rostislav Developement of Bioinformatics Server (Faculty of Informatics, 2008-2010)
Dvorak Pavel Directed Evolution of Haloalkane Dehalogenase DhaA towards Increased
Activity with 1,2-dichloroethane (Department of Microbiology, 2008-2009)
Polinek Jiri Fermentative Production of Haloalkane Dehalogenases (Department of Microbiology, 2008-2009)
Pavelka Antonin HotSpot
Wizard – Tool for Selection of Protein Engineering Hot Spots (Faculty of Informatics, 2007-2008)
Stepankova Veronika Medium Engineering of Haloalkane Dehalogenase Catalysis: Effect of Water-Miscible Organic Solvents (Department of Biochemistry, 2005-2008)
Holub Peter Protein Engineering of Haloalkane Dehalogenase LinB: Towards the Change of Reaction Mechanism (Department of Biochemistry, 2006-2008)
Jerabek Petr Molecular Modeling of Enantioselectivity of Haloalkane Dehalogenase LinB (Department of Biochemistry, 2005-2007)
Bidmanova Sarka Development and Construction of Biosensors for Detection of Halogenated Compounds in the Environment (Department of Microbiology, 2005-2007)
Brezovsky Jan Computer-Assisted Study of Enzymatic Dehalogenation of DDT (Department of Biophysics, 2005-2006)
Klvana Martin Computer Modelling of Bacterial Enzymes Involved in Degradation of Halogenated Hydrocarbons (Department of Microbiology, 2002-2004)
Tesinska Iva Mycobacterial Haloalkane Dehalogenases Rv2296 and Rv2579 (Department of Biochemistry, 2002-2004)
Dobes Petr Structure-Function Characterization of the Elicitin Cryptogein (Department of Biochemistry, 2001-2003)
Budova Martina Exprese, purifikace a kineticka charakterizace haloalkan dehalogenas (Department of Biochemistry, 2001-2002)
Jedlicka Tomas Pocitacove modelovani enzym-substrat komplexu haloalkan dehalogenaz (Department of Environmental Sciences and Ecotoxicology, 2000-2003)
Strouhal Michal Screening of Genes rv2579, rv2296 and dhmA in Isolates of M. bovis, M. avium a M. paratuberculosis (Department of Microbiology, 2000-2003)
Monincova Marta Study of Kinetics of Microbial Dehalogenation Reactions (Department of Microbiology, 2000-2002)
Marvanova Sona Biochemical Characterization of Mutant Haloalkane Dehalogenases (Department of Environmental Sciences and Ecotoxicology, 1999-2001)
Czernekova Vladka Purification of Dehalogenase from Bacterium Mycobacterium avium (Department of Biochemistry, 1999-2001)
Slanina Michal Hydrolytic Dehalogenation of Unsaturated Aliphatic Hydrocarbons (Department of Environmental Sciences and Ecotoxicology, 1998-1999)
Bohac Michal Computer Modelling of Dehalogenation Reactions of Haloalkane Dehalogenases (Department of Environmental Sciences and Ecotoxicology, 1997-2000)
Prokop Martin TRITON – Visualization Software for Study of Enzymatic Reactions (Department of Organic Chemistry, 1995-1997)
Hynkova Kamila Estimation of Steady-State Constants of Haloalkane Dehalogenase LinB for Group of Halogenated Hydrocarbons (Department of Environmental Sciences and Ecotoxicology, 1995-1997)
Jesenska Andrea Study of Structure-Biodegradability Relationships for Halogenated Aliphatic Hydrocarbons (Department of Microbiology, 1995-1997)
Blaha Ludek Applications of Bioluminiscence Test (Department of Microbiology, 1994-1996)

David to Participate in NGSchool2022
Stas to Present at AI for Enzyme Instructed Synthetic Catalysis
David to Present at XXV Biological Days
1st Droplet Sorting in LL
Jiri to Present at Business2Science
Prof. Bornscheuer to Give Lecture at MU
Dean’s Award for Pavel