Diploma Theses
| Name | Thesis |
|---|---|
| Kapustova Linda | Identification and Study of Potential Drugs Targeting Apolipoprotein E4 in Alzheimer’s Disease Using Molecular Modelling Methods (Bioinformatics, Department of Biochemistry, 2024-2025) |
| Svobodova Lucie | Web Application for the Search of Related Enzymes (FIT VUT, 2024-2025) |
| Pailozian Karen | Prediction of Protein Stability by Advanced Machine Learning Methods (Bioinformatics, Department of Biochemistry, 2023-2025) |
| Kabourek Petr | LLWS: Multi-Platform Framework for Distributed Calculation and Its Integration in Fireprotweb 2 a Web-Based Platform for Design of Thermostable Proteins (Department of Computer Systems and Communications, FI MU, 2023-2025) |
| Havlasek Martin | Development of a Strategy for the Suppression of Protein Aggregation and Its Application to the Dehalogenase LinB (Department of Biochemistry, 2023-2025) | Orel Vojtech | Kinetic Mechanism of NanoLuc Luciferase (Department of Biochemistry, 2022-2024) |
| Kopriva Martin | Application of Microfluidics in Development of Drugs against Alzheimer’s Disease (Department of Biochemistry, 2022-2024) |
| Lacko David | Machine Learning-based Prediction of Mutational Effects on Protein Immunogenicity (FIT VUT, 2020-2024) |
| Berezny Matej | Benchmark of the Computational Tools for the Prediction of the Effect of Mutations on Protein Stability (FIT VUT, 2022-2024) |
| Rosinska Monika | Prediction of the Effect of Mutations on Protein Stability (FIT VUT, 2022-2024) |
| Smrckova Anna | Structural and Biochemical Characterization of the |
| Borko Simeon | Analysis of Cancer-Associated Protein Mutations (Department of Information Systems, FIT VUT, 2020-2023) |
| Pluskal Daniel | Engineering of a Macromolecular Bioluminescence Resonance Energy Transfer Complex (Department of Biochemistry, 2021-2023) |
| Faldynova Hana | Study of the Effect of Mutations on Protein Solubility (Department of Molecular Biology and Genetics, 2021-2023) |
| Kohout Petr | Identification of the Protein Tunnels using Molecular Dynamics (Department of Information Systems, FIT VUT, 2020-2022) |
| Kohout Pavel | Application of Variational Autoencoders for Ancestral Sequence Reconstruction (Department of Computer Systems, FIT VUT, 2020-2022) |
| Bubenik Michal | Machine-Learning based Prediction of Substrate Specificity Profiles for Haloalkane Dehalogenases (RECETOX, 2020-2022) |
| Slanska Michaela | Kinetic Mechanism of Fluorinase from Bacterium Streptomyces sp. MA37 (Department of Biochemistry, 2020-2022) |
| Slanska Katerina | Study of Protein Solubility (Department of Experimental Biology, 2019-2021) |
| Horackova Jana | Prediction of Stable Proteins (Department of Biochemistry, 2019-2021) |
| Dobias Adam | PredictSNP Onco: Web Server for Automatic Analysis of Oncology-Based Mutations (Department of Biochemistry, 2018-2021) |
| Velecky Jan | Prediction of the Effect of Mutation on Protein Solubility Using Electrostatic Potential (Department of Computer Systems, FIT VUT, 2018-2020) |
| Vasina Michal | High-throughput Characterization of Novel Biocatalysts by Using Microfluidics (Department of Biophysical Chemistry, 2017-2019) |
| Solansky Pavel | Application of Microfluidics in Metabolic Engineering (Department of Experimental Biology, 2016-2018) |
| Toul Martin | Kinetic Mechanism of Coelenterazine-Dependent Luciferase Reaction (Department of Biochemistry, 2016-2018) |
| Dockalova Veronika | Development of Fluorescent Substrates for Enzymology (Department of Biophysics, 2016-2018) |
| Dunajova Zuzana | Computational Engineering of Enzymes with Buried Active Sites (Department of Structural Chemistry, 2015-2018) |
| Markova Klara | Structural and Functional Characterization of Selected Haloalkane Dehalogenase Variants (Department of Special Biology, 2016-2018) |
| Stourac Jan | Software Tool for Automated Design of Mutations and Smart Libraries for Protein Engineering (Department of Bioinformatics, 2015-2017) |
| Vavra Ondrej | Methods for Identification of Biologically Relevant Tunnels in Proteins (Department of Genomics and Proteomics, 2015-2017) |
| Kunka Antonin | Structural Base of Protein Stabilisation (Department of Biochemistry, 2014-2016) |
| Musil Milos | Predictor of the Effect of Amino Acid Substitutions on Protein Function (Department of Information Systems, Brno University of Technology, 2014-2015) |
| Szelcsanyiova Petra | Biochemical Characterization of Haloalkane Dehalogenases with Modified Tunnels (Department of Microbiology, 2012-2014) |
| Buryska Tom | Development of Dehalogenase Inhibitors – Potential Antituberculotics (Department of Biochemistry, 2011-2013) |
| Neuwirth Ondrej | Development of Inhibitors of Dehalogenases – Potential Antituberculotics (Department of Biochemistry, 2010-2013) |
| Chrast Lukas | Characterization of Novel Biocatalysts from Extremophilic Bacteria (Department of Microbiology and Molecular Biotechnology, 2010-2012) |
| Drienovska Ivana | Biochemical Characterization of the First Haloalkane Dehalogenase DpcA Isolated From Extremophilic Organism (Department of Biochemistry, 2011-2012) |
| Daniel Lukas | In Silico Study of Substrate Specificity of Haloalkane Dehalogenases (Department of Biochemistry, 2009-2011) |
| Wolny Rostislav | Developement of Bioinformatics Server (Faculty of Informatics, 2008-2010) |
| Dvorak Pavel | Directed Evolution of Haloalkane Dehalogenase DhaA towards Increased Activity with 1,2-dichloroethane (Department of Microbiology, 2008-2009) |
| Polinek Jiri | Fermentative Production of Haloalkane Dehalogenases (Department of Microbiology, 2008-2009) |
| Pavelka Antonin | HotSpot Wizard – Tool for Selection of Protein Engineering Hot Spots (Faculty of Informatics, 2007-2008) |
| Stepankova Veronika | Medium Engineering of Haloalkane Dehalogenase Catalysis: Effect of Water-Miscible Organic Solvents (Department of Biochemistry, 2005-2008) |
| Holub Peter | Protein Engineering of Haloalkane Dehalogenase LinB: Towards the Change of Reaction Mechanism (Department of Biochemistry, 2006-2008) |
| Jerabek Petr | Molecular Modeling of Enantioselectivity of Haloalkane Dehalogenase LinB (Department of Biochemistry, 2005-2007) |
| Bidmanova Sarka | Development and Construction of Biosensors for Detection of Halogenated Compounds in the Environment (Department of Microbiology, 2005-2007) |
| Brezovsky Jan | Computer-Assisted Study of Enzymatic Dehalogenation of DDT (Department of Biophysics, 2005-2006) |
| Klvana Martin | Computer Modelling of Bacterial Enzymes Involved in Degradation of Halogenated Hydrocarbons (Department of Microbiology, 2002-2004) |
| Tesinska Iva | Mycobacterial Haloalkane Dehalogenases Rv2296 and Rv2579 (Department of Biochemistry, 2002-2004) |
| Dobes Petr | Structure-Function Characterization of the Elicitin Cryptogein (Department of Biochemistry, 2001-2003) |
| Budova Martina | Exprese, purifikace a kineticka charakterizace haloalkan dehalogenas (Department of Biochemistry, 2001-2002) |
| Jedlicka Tomas | Pocitacove modelovani enzym-substrat komplexu haloalkan dehalogenaz (Department of Environmental Sciences and Ecotoxicology, 2000-2003) |
| Strouhal Michal | Screening of Genes rv2579, rv2296 and dhmA in Isolates of M. bovis, M. avium a M. paratuberculosis (Department of Microbiology, 2000-2003) |
| Monincova Marta | Study of Kinetics of Microbial Dehalogenation Reactions (Department of Microbiology, 2000-2002) |
| Marvanova Sona | Biochemical Characterization of Mutant Haloalkane Dehalogenases (Department of Environmental Sciences and Ecotoxicology, 1999-2001) |
| Czernekova Vladka | Purification of Dehalogenase from Bacterium Mycobacterium avium (Department of Biochemistry, 1999-2001) |
| Slanina Michal | Hydrolytic Dehalogenation of Unsaturated Aliphatic Hydrocarbons (Department of Environmental Sciences and Ecotoxicology, 1998-1999) |
| Bohac Michal | Computer Modelling of Dehalogenation Reactions of Haloalkane Dehalogenases (Department of Environmental Sciences and Ecotoxicology, 1997-2000) |
| Prokop Martin | TRITON – Visualization Software for Study of Enzymatic Reactions (Department of Organic Chemistry, 1995-1997) |
| Hynkova Kamila | Estimation of Steady-State Constants of Haloalkane Dehalogenase LinB for Group of Halogenated Hydrocarbons (Department of Environmental Sciences and Ecotoxicology, 1995-1997) |
| Jesenska Andrea | Study of Structure-Biodegradability Relationships for Halogenated Aliphatic Hydrocarbons (Department of Microbiology, 1995-1997) |
| Blaha Ludek | Applications of Bioluminiscence Test (Department of Microbiology, 1994-1996) |